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Renal Impairment: There is limited information on the pharmacokinetics of bupropion in zyban patients with renal impairment .
An inter-study comparison between normal subjects zyban nz zyban side effects zyban withdrawal symptoms zyban depression how much does zyban cost buy and patients Reference ID: 3004634 with end-stage renal failure demonstrated that the parent drug Cmax and AUC values were comparable in the 2 groups, whereas the hydroxybupropion and threohydrobupropion metabolites had a 2 . 8-fold increase, respectively, in AUC for patients with does zyban work champix zyban zyban dosage zyban for depression uk is zyban an antidepressant zyban end-stage renal failure . 3- and bupropion zyban quit smoking medication zyban zyban to quit smoking zyban antidepressant zyban 150 2 .
9 zyban canada zyban half life what is the difference between zyban and wellbutrin wellbutrin and ± 10 . 8 mL/min) showed that exposure to a single 150-mg dose of sustained-release bupropion was approximately 2-fold higher in patients with impaired renal function while levels of the hydroxybupropion and threo/erythrohydrobupropion (combined) metabolites were zyban similar in the 2 groups . A second study, comparing normal subjects and patients with moderate-to-severe zyban instructions zyban and alcohol zyban over the counter zyban price zyban pregnancy zyban india renal impairment (GFR 30 .
Bupropion is extensively metabolized in the liver to active metabolites, which are further metabolized and subsequently excreted by the zyban kidneys .
ZYBAN should be used with caution in patients with renal impairment and a reduced zyban frequency of dosing should be considered as bupropion and the metabolites of bupropion may accumulate in such patients to a greater extent than usual .
The patient should be closely monitored for possible zyban adverse effects that could indicate high drug or metabolite levels .

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