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Usage of doxycycline:
]): 20 mg twice daily as an adjunct doxycycline following scaling and root planing; may treat for up to 9 -Periodontitis, refractory (unlabeled use): Oral: 100-200 mg daily (Jolkovsky, 2006) -Proctitis: Oral: 100 mg twice daily for 7 days (in combination with ceftriaxone) (CDC, -Acute: 100 mg every 12 hours for 14 days (CDC, 2013); Note: In patients who have valvular heart disease, consider increasing the duration of therapy to 1 year and adding hydroxychloroquine to the regimen to prevent endocarditis; consultation with an infectious disease expert is recommended (CDC, 2002; Fenollar, 2001) . dose of cefoxitin (plus oral probenecid) or ceftriaxone doxycycline (CDC, 2010) -Periodontitis: Oral (Periostat® [Canadian availability; not available in the U .
-Chronic doxycycline (CDC, 2013): -Endocarditis or vascular infection: 100 mg every 12 hours in combination with hydroxychloroquine for ≥18 months -Noncardiac organ disease: 100 mg every 12 hours in combination with hydroxychloroquine (duration based on serologic response; ID consult -Postpartum with serologic evidence present >12 months after delivery: 100 mg every 12 hours in combination with hydroxychloroquine for 12 months -Rosacea Oral (Oracea® [U .
: 100 mg twice daily for 5-7 days; severe or complicated disease may require longer treatment; human granulocytotropic anaplasmosis (HGA) should be treated doxycycline for 10-14 days . labeling], Apprilon™ [Canadian labeling]): 40 mg once daily in the morning -Sclerosing agent for pleural effusion (unlabeled use): Intrapleural: 500 mg as a single dose in 100 mL NS (Porcel, 2006); may require a repeat dose (Kvale, 2007) -Primary/secondary syphilis: Oral: 100 mg twice doxycycline daily for 14 days (CDC, 2010) -Latent syphilis: Oral: 100 mg twice daily for 28 days (CDC, 2010) -Tickborne rickettsial disease: Oral, I .
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