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It is recommended as a first-line treatment of pain associated hydrocodone acetaminophen side effects constipation acetaminophen nyquil acetaminophen gastritis with osteoarthritis .
The mechanism of action is complex and includes the effects of both the peripheral (COX inhibition), and central (COX, serotonergic acetaminophen dosage infants 160mg acetaminophen normal dose range acetaminophen gummies descending neuronal pathway, L-arginine/NO pathway, cannabinoid system) antinociception processes and ìredoxî mechanism .
Paracetamol is well tolerated drug and produces few side effects from the gastrointestinal tract, however, despite that, every year, has seen a steadily increasing number of registered cases of paracetamol-induced liver intoxication acetaminophen all over the world .
Given the growing problem of the safety of acetaminophen is questioned acetaminophen the validity of the sale of the drug without a prescription .
This work, in conjunction with the latest reports on the mechanism of action of paracetamol, trying to point out that it is not a panacea devoid of side effects, and indeed, especially when is taken regularly and in large doses (> 4 g/day), there is a risk of serious acetaminophen toxicity chart acetaminophen caffeine acetaminophen dangers hydrocodone acetaminophen side effects .
Keywords: paracetamol, acetaminophen, toxic effects, mechanism of action, cyclooxygenase, cannabinoid, serotonergic, prostaglandin-endoperoxide acetaminophen synthases Paracetamol (an international name used in Europe) and acetaminophen (an international name used in the USA) are two official names of the same chemical compound derived from its chemical name: N-acetyl-para-aminophenol (the segment ëícetíí inserted between ëíparaíí and ëíaminoíí) and Nacetyl-para-aminophenol .
This drug acetaminophen has a long history and, as it often happens with important discoveries, it was found by chance .

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