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The most common ( ? 2% more frequent than low-dose 50 mg/day TOPAMAX� ) adverse reactions resulting in discontinuation in this trial were difficulty with concentration/attention, fever, flushing, and can topamax cause depression topamax 100 mg weight loss is topiramate the same as topamax how to confusion .
Table 5: Incidence (%) of Treatment-Emergent Adverse Reactions in topamax Monotherapy Epilepsy Where the Incidence Was at Least 2% in Any TOPAMAX� Group and the Incidence in the 400 mg/day TOPAMAX� Group Was Greater Than the Incidence in the 50 mg/day TOPAMAX� Group for Adults ( ? 16 Years) and Pediatric (6 to < 16 Years) Patients in Study TOPMAX-EPMN-106 TOPAMAX� Daily Dosage Group (mg/day) The most commonly observed adverse reactions associated with the use of TOPAMAX� at dosages of 200 to 400 mg/day (recommended dose range) in controlled trials in adults with partial onset seizures, primary generalized tonic-clonic seizures, or Lennox-Gastaut syndrome, that were seen at an incidence higher ( ? 5%) than in the placebo group were : somnolence, weight decrease, anorexia, dizziness, ataxia, speech disorders and related speech problems, language problems, psychomotor slowing, confusion, abnormal vision, difficulty with memory, paresthesia, diplopia, nervousness, and asthenia (see Table 6) .
Dose-related adverse reactions at dosages of 200 to 1,000 mg/day topamax are shown in Table 8 .
The most commonly observed adverse reactions associated with the use of TOPAMAX� at dosages of 5 to 9 mg/kg/day in controlled trials in pediatric patients with partial onset seizures, primary generalized tonic-clonic seizures, or Lennox-Gastaut syndrome, that were seen at an incidence higher ( ? 5%) than in the placebo group were : fatigue, somnolence, topamax anorexia, nervousness, difficulty with concentration/attention, difficulty with memory, aggressive reaction, and weight decrease (see Table 9) .

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